Arizona Cardinals vs San Francisco 49ers free live stream, odds, time, TV channel, watch Monday Night Football online (11/21/2022)

The Arizona Cardinals meet the San Francisco 49ers in Mexico City on Monday Night Football. The Cardinals have won 11 of the past 14 games in the series. The 49ers have allowed zero points in the second half of their past two games. This NFC West rivalry is set to kick off on Monday, November 21 at 5:15 p.m. PT/8:15 p.m. ET with a live national TV broadcast on ESPN.

• You can watch the Cardinals vs. 49ers game live for FREE with fuboTV (free trial) or with Sling (free trial), or follow along with our live updates and see more live streaming and TV options for this game provided below.


Moneyline: SF -350 | ARI +280

Spread: SF -8 | ARI +8

O/U: 43

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Prediction: San Francisco 23, Arizona 15


What: The Arizona Cardinals take on the San Francisco 49ers on Monday Night Football in NFL Week 11.

When: Monday, November 21 at 5:15 p.m. PT/8:15 p.m. ET

Where: Estadio Azteca | Mexico City


How to watch the game live online for free: You can watch the game live for FREE with fuboTV (free trial). You can also get this game DirecTV Stream (free trial) or Sling TV (promotional offers), if you prefer those platforms and their pricing plans. If you already have a cable provider, use your login information to watch this game on Watch ESPN.

Channel finder, more ways to watch: Verizon Fios, AT&T U-verse, Comcast / Xfinity, Spectrum/Charter, Optimum/Altice, Cox, DIRECTV, Dish.


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